Syntopia combines advanced 3D cell culture, organoids, and innovative microfluidics to help to biotech and pharmaceutical industries generate high-quality biological data at scale - accelerating research and reducing clinical failure rates
In drug discovery, over 90% of drug candidates fail in clinical trials.
Traditional models - 2D cell cultures and animal testing - poorly predict human biology, driving huge costs and delays for biotech and pharma
Syntopia brings together physiologically relevant 3D biology and a breakthrough microfluidic platform to generate better preclinical data, cheaper and faster
3D cell culture & organoids
Scaffold-based tissue models with long-term viability and functional assays
Innovative microfluidics
Pump-free, open format, fully compatible with robotics - enabling high-throughput experiments and large-scale data generation without specialized instruments
Multi-modal readouts
Immunofluorescence imaging, secretome chemical analysis, and RNA sequencing after treatment - delivering a comprehensive view of cell responses
Datasets of unmatched quality for AI-driven biomarker detection, drug response prediction, and virtual cohort creation
Our solution is modular - we can adapt the device design and assay configuration to meet specific application needs.
Current focus on three applications:
Patient-derived tumoroids / organoids with immune cell co-culture
Enables functional studies: migration, cytotoxicity, CAR-T/CAR-NK screening
Primary Human Hepatocyte model, viable > 21 days
Enables robust datasets for in silico toxicity prediction
Brain microenvironment organoids integrating microglia
Supports personalized medicine and early-stage neurotoxicology